https://bugzilla.mozilla.org/show_bug.cgi?id=1570168 is something I've needed for a long time. It's getting really tedious as the years go by to keep turning groups of extensions on and off (e.g. all the privacy extensions have to be off or I can't log in to my bank, etc. and as OP notes, there are many more examples). Doesn't look like there's been any action on this since it was added as a request, and it would be great to get it implemented.
Apologies if "New Idea" wasn't the right way to plug for what I want, but Bugzilla doesn't seem to have an upvote capability, and there didn't seem to be an appropriate category here either, so I did the best I could. If there's somewhere else I should have posted this, I'd be grateful if a mod could please shunt it that way with a note so I know what to do next time.