Setting permissions.default.image to '2' ("never load") is pretty useful in a cultural environment of prolific use of disgusting or unnecessary images. However, while reading and researching, sometimes it would be advantageous for the browser to be able to load an image pointed by the user, instead of the user having to download the linked image file to open it and only then being able to see the image for its contents.
The value '2' in permissions.default.image means the browser will never load images, not even directly acessed by remote URLs, only local (file://etc); the value '0' makes the browser to only load images from the same source as the webpage. In both cases a load-once button in the image space can be pretty useful.
Use case scenario: set permissions.default.image to '2' and search Wikipedia for a map. Click the load button in the images whose labels indicate they can be the map you are searching for.