Support for Delta.Chat would be grand!
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chat via e-mail as in Delta Chat
There is a project called Delta Chat that use e-mail to emulate chat : https://delta.chat/en/help
It natively supports end-to-end encryption with Autocrypt and presents exchanges by recipients, in the form of a chat. It is probably possible to offer the same thing directly integrated into Thunderbird.
Use Thunderbird Chat same way https://delta.chat application.
The subject speaks by itself.
(Note: similar ideas have been merged into this thread)